MR spectroscopy detects lipid peaks in cerebrotendinous xanthomatosis.
نویسندگان
چکیده
CTX is a rare lipid-storage disease. Novel MRS findings from 3 patients, using a short TE, were the presence of lipid peaks at 0.9 and 1.3 ppm in the depth of the cerebellar hemisphere; this might represent an additional marker of disease that is CNS-specific and noninvasive. A decrease in NAA concentration was also detected and attributed to neuroaxonal damage. One patient presented an increase in mIns concentration, pointing to gliosis and astrocytic proliferation.
منابع مشابه
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عنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 31 7 شماره
صفحات -
تاریخ انتشار 2010